von Willebrand disease

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von Willebrand disease

Postby Margaret » Sun Jun 15, 2014 6:46 pm

Last year I wanted to have my GSP checked for this and was unable to have a test done as both NZ and Australia don't send these tests away anymore, I think it was they were getting unreliable readings or something.

Can you still get the tests done? I just find this strange.
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Re: von Willebrand disease

Postby 3drahthaars » Mon Jun 16, 2014 7:34 am

Always had mine done at Cornell U. I think there's a genetic test now though

Good luck,

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Re: von Willebrand disease

Postby lanco » Mon Jun 16, 2014 8:45 am

I will find out more from resources at work later this week, but I'm not sure the genetic test is readily available for vWD 2 which is what you are looking for. ELISA for the factor is available but some dog's results can be indeterminate. It's just that there is overlap in the normal and abnormal population, not a problem with testing accuracy.
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Re: von Willebrand disease

Postby 3drahthaars » Mon Jun 16, 2014 9:35 am

lanco wrote:I will find out more from resources at work later this week, but I'm not sure the genetic test is readily available for vWD 2 which is what you are looking for. ELISA for the factor is available but some dog's results can be indeterminate. It's just that there is overlap in the normal and abnormal population, not a problem with testing accuracy.


There are several issues with the ELISA... sample collection, and handling of samples, to name a few. Indeterminate is just that, neither positive or negative. I had a litter out of a dog that tested borderline or indeterminate that tested all negative.

We had issues with independent labs and just stuck with Dr. Brooks and Cornell U. If you follow their instructions to the "T", usually the tests results are accurate.

Good luck in your search in the lower hemisphere.

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Re: von Willebrand disease

Postby Margaret » Mon Jun 16, 2014 7:25 pm

Thanks. That might be the problem, not sending in good enough samples.

Will ask my vet to check on the Cornell University.
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Re: von Willebrand disease

Postby DrahtsundBraats » Mon Jun 16, 2014 10:03 pm

http://www.vetgen.com/

Order the swab, follow directions and you'll have the results in 3-4 weeks.

Bob is right about the serum test and we all owe Dr. Brooks a big thumbs up for her work over the years. The only difficulty with the serum test can be the quality of the blood sample...but done right it works.
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Re: von Willebrand disease

Postby Margaret » Mon Jun 16, 2014 11:24 pm

Thanks for that.
I've emailed them.

Name rings a bell though, maybe it was them that the vets used originally, i'll find out.
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Re: von Willebrand disease

Postby Margaret » Tue Jun 17, 2014 5:15 pm

That was good service, fast reply. They will send me a kit will cost NZ$110 which is cheaper than the vet cost was going to be.
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Re: von Willebrand disease

Postby CohanseyDD » Thu Jun 19, 2014 8:22 am

I used VetGen for all of mine.
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Re: von Willebrand disease

Postby Margaret » Thu Jun 19, 2014 5:20 pm

I think it was Vetgen that the vets here in NZ sent swabs to but stopped because of ??

I've been recommended Labolink in UK.
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Re: von Willebrand disease

Postby DDGUY » Mon Jun 23, 2014 6:56 am

The DNA test for vWD Type II was developed at Utrecht University in the Netherlands, and has been around for quite a few years. Laboklin in Germany also offeres the test, and I believe they now offer it with a cheek swab, but also offered it with a dried blood card in the past. For DD it can also be done at Hannover University through Dr. Otmar Distl. It is pretty reasonable through Hannover and you can also add the Roughhaar DNA test for about the same price.
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